Spring is in the air—but so are allergens. For people with autoimmune conditions like Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Lupus, seasonal allergies can do more than just cause sneezing and itchy eyes. They may trigger inflammation, worsen symptoms, and make autoimmune flares more frequent.
Understanding the connection between allergies and autoimmune diseases is key to managing symptoms and maintaining a better quality of life during the spring months.
The Link Between Allergies and Autoimmune Conditions
Spring allergies, also known as seasonal allergic rhinitis, occur when the immune system overreacts to pollen, mold spores, or other airborne irritants. This reaction releases histamines and inflammatory cytokines, which can increase overall inflammation in the body.
For individuals with autoimmune diseases—where the immune system is already in overdrive—this additional immune response can worsen joint pain, fatigue, and inflammation.
How Allergies Can Affect Autoimmune Flares
- Increased Inflammation – Allergy-induced inflammation can exacerbate joint pain, swelling, and stiffness, especially in conditions like RA, PsA, and Lupus.
- Immune System Overload – The immune system is already misfiring in autoimmune diseases, and seasonal allergies add another layer of immune activation, making symptoms harder to control.
- Fatigue and Brain Fog – Histamines, cytokines, and the body’s immune response can contribute to chronic fatigue, brain fog, and worsened autoimmune symptoms.
- Medication Interactions – Some over-the-counter allergy medications, like antihistamines and decongestants, may interact with common autoimmune treatments, such as steroids or immunosuppressants.
Tips to Manage Spring Allergies Without Worsening Autoimmune Symptoms
Limit Exposure to Allergens
- Check daily pollen counts and try to stay indoors on high-pollen days.
- Keep windows closed and use HEPA filters in your home and car.
- Shower and change clothes after spending time outdoors to remove pollen from your skin and hair.
Choose Autoimmune-Friendly Allergy Medications
- Non-drowsy antihistamines like loratadine (Claritin) or fexofenadine (Allegra) are often safer options.
- Nasal sprays like fluticasone (Flonase) or azelastine (Astelin) can reduce allergy symptoms without systemic immune effects.
- Always consult your doctor before starting a new medication, especially if you’re on immunosuppressive therapy.
Support Your Immune System Naturally
- Anti-inflammatory diet – Increase intake of omega-3 fatty acids, turmeric, ginger, and leafy greens.
- Stay hydrated – Helps flush allergens from your system.
- Manage stress – High stress can weaken immune function and contribute to autoimmune flares.
Talk to a Rheumatology Specialist If Symptoms Worsen
If you’re noticing more joint pain, stiffness, or fatigue during allergy season, it may not just be allergies—it could be an autoimmune flare. A rheumatologist can help adjust your treatment plan to reduce inflammation and prevent long-term damage.
Find Relief This Allergy Season with Expert Care
At OrthoArkansas, our team of rheumatology specialists understands the unique challenges of managing autoimmune conditions during allergy season. If you’re experiencing increased inflammation, joint pain, or fatigue this spring, schedule an appointment with our experts to create a customized treatment plan that works for you.
